Worm Research Lab

McMaster University

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 ===== Overview ===== ===== Overview =====
 {{ :​images:​worms.jpg?​250|}} {{ :​images:​worms.jpg?​250|}}
-Research in Gupta Lab focuses on key biological processes related to Cell Signalling, Cell Proliferation and Cell Differentiation. The questions of our interest are:+Research in Gupta Lab focuses on key biological processes related to Cell Signalling, Cell Proliferationand Cell Differentiation. The questions of our interest are:
  
   * How cells respond to external signals,   * How cells respond to external signals,
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   * How environmental signals modulate animal behavior   * How environmental signals modulate animal behavior
  
-These questions form the basis of our work to understand the mechanisms of normal processes and diseases, such as cancer and neuronal degeneration. For this we are using two well-known ​nematode ​(worm) model organisms //C. elegans// and //C. briggsae//. These tiny animals (roughly 1 mm long) are particularly useful in discovering the roles of conserved genes and pathways in processes that are shared among all eukaryotes.\\+These questions form the basis of our work to understand the mechanisms of normal processes and diseases, such as cancer and neuronal degeneration. For this we are using two well-known ​nematodes ​(worm) model organisms //C. elegans// and //C. briggsae//. These tiny animals (roughly 1 mm long) are particularly useful in discovering the roles of conserved genes and pathways in processes that are shared among all eukaryotes.\\
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 Our approach is multidisciplinary and includes techniques in genetics, genomics, molecular biology, bioinformatics,​ and engineering. We collaborate extensively with other laboratories,​ both at McMaster and outside, to develop new tools and resources. The applied aspect of our work involves making use of basic research findings and in-house tools to carry out drug discovery projects.\\ Our approach is multidisciplinary and includes techniques in genetics, genomics, molecular biology, bioinformatics,​ and engineering. We collaborate extensively with other laboratories,​ both at McMaster and outside, to develop new tools and resources. The applied aspect of our work involves making use of basic research findings and in-house tools to carry out drug discovery projects.\\
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-Research projects in our lab are currently funded by Natural Sciences and Engineering Research Council of Canada (NSERC). In previous years we were also supported by Canadian Institutes of Health Research (CIHR), Ontario Ministry of Research and Innovation (MRI), Canadian Research Chairs (CRC), Canada Foundation for Innovation (CFI), Ontario Innovation Trust (OIT), and National Institutes of Health (NIH).\\+Research projects in our lab are currently funded by the Natural Sciences and Engineering Research Council of Canada (NSERC). In previous years we were also supported by Canadian Institutes of Health Research (CIHR), Ontario Ministry of Research and Innovation (MRI), Canadian Research Chairs (CRC), Canada Foundation for Innovation (CFI), Ontario Innovation Trust (OIT), and National Institutes of Health (NIH).\\
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-Please feel free to contact us if you have any questions, comments and feedback. Thank you!\\+Please feel free to contact us if you have any questions, commentsand feedback. Thank you!\\
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 <color grey>​Department of Biology\\ <color grey>​Department of Biology\\
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